When rats were injected having a chemical much like marijuana s primary component, THC, soon after a going through a seriously demanding event, they demonstrated a substantial decrease in signs and symptoms like individuals observed in individuals with publish-distressing stress disorder. The study�tested�a�synthetic cannabinoid known as WIN 55,212-2, that was injected into the creatures amygdala,�a brain region active in the unsafe effects of feelings like anxiety and stress. Timing was important.�Rats because of the drug two and 24 hrs following the stress factor having to go swimming for fifteen minutes made an appearance less traumatized when examined not much later, in comparison with individuals because of the drug 48 hrs later or given no drug whatsoever.�While the research increases the already large and sophisticated pile of evidence the cannabinoid system has an important role in controlling feelings like anxiety, this is not even close to showing that cannabinoids is going to be helpful for dealing with Post traumatic stress disorder in humans.
Regrettably, just about any story since the study first got it wrong�by recommending that (e.g., Marijuana blocks publish-distressing stress Marijuana blocks Post traumatic stress disorder signs and symptoms in rats. ). And several, otherwise most tales, confused the synthetic THC mimic analyzed with THC or marijuana itself. While WIN 55,212-2 binds towards the same receptor as THC, CB1, it features a completely different structure. This research contributes to some previous ones recommending that cannabinoids might help treat Post traumatic stress disorder (as could other controlled substances like ecstasy, or MDMA), but you will find still lots of hurdles to mix before concluding this can result in effective Post traumatic stress disorder treatment.
Reference:�Eti Ganon-Elazar, Irit Akirav. Cannabinoids Prevent the introduction of Behavior and Endocrine Modifications inside a Rat Type of Intense Stress. Neuropsychopharmacology, 2011 DOI: 10.1038/npp.2011.204
Image: cheesechoker�/ Flickr
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